1348 Changes in the aging dermal hair follicle environment in female scalp
نویسندگان
چکیده
منابع مشابه
Hair follicle dermal cells repopulate the mouse haematopoietic system.
Skin and hair follicle stem cell biology is the focus of increasing interest, not least because the adult hair follicle has well defined dermal and epithelial populations that display distinct developmental properties. Recent evidence suggests that a number of adult cell populations have much broader stem cell capabilities than previously thought. To examine whether this applied to the hair fol...
متن کاملDissociated human dermal papilla cells induce hair follicle neogenesis in grafted dermal-epidermal composites
Cells. Human dermal papilla cells isolated from temporal scalp dermis (Promocell, Heidelberg, Germany) from five female donors (HDP41, HDP43, HDP44, HDP47, and HDP52) and one male donor (HDP60), named according to donor age in years, were propagated in vitro according to manufacturer’s recommendations. Keratinocytes were isolated from neonatal foreskins and were cultured in serum-free medium (K...
متن کاملAging in hair follicle stem cells and niche microenvironment.
Hair graying and hair loss are prominent and common characteristics of the elderly population. In some individuals these processes can significantly impact their quality of life, leading to depression, anxiety and other serious mental health problems. Accordingly, there has been much interest in understanding the complex physiological changes within the hair follicle in the aging individual. It...
متن کاملHair follicle dermal papilla cells at a glance.
Ryan R. Driskell1, Carlos Clavel2, Michael Rendl2,* and Fiona M. Watt1,3,* 1Laboratory for Epidermal Stem Cell Biology, Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge CB2 1QR, UK 2Black Family Stem Cell Institute and Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, NY 10029, USA 3CRUK Cambridge Research Institute, ...
متن کاملBalding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp.
Androgens can gradually transform large scalp hair follicles to smaller vellus ones, causing balding. The mechanisms involved are unclear, although androgens are believed to act on the epithelial hair follicle via the mesenchyme-derived dermal papilla. This study investigates whether the levels and type of androgen receptors in primary lines of cultured dermal papilla cells derived from balding...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2018
ISSN: 0022-202X
DOI: 10.1016/j.jid.2018.03.1365